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- DOI 10.18231/j.ijcap.2019.033
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CrossMark
- Citation
Breathanalysis of expired carbonmonoxide and its correlation with symptoms of toxicity among urban automobile drivers
- Author Details:
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Chitra M *
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Baskara Amsath Raja R
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M Semmal
Introduction: Automobile emissions form the leading cause of air pollution in urban areas. Carbonmonoxide (CO) is one among the six major pollutants of air caused by vehicles. Because it is colourless, odourless and tasteless gas, exposure can cause symptoms which can be unobserved. Drivers are at risk as exposure is maximum, posing an occupational hazard.
Aim: To screen the urban automobile drivers for exhaled breath Carbonmonoxide (eCO) and to correlate eCo with symptoms experienced that may be due to CO exposure.
Materials and Methods: A cross sectional observation of Breathanalysis of automobile drivers (n=101) for expired CO (eCO) was done using CO Breathanalyser (Vitalograph 29700). Data regarding age, duration of exposure, hours spent in driving per day, other sources of exposure such as smoking status, history of passive smoking, exposure to coal fire in the household, place of work were obtained. Symptoms pertaining to CO exposure like headache, body pain, tiredness, and visual disturbances like irritation of eye, redness, neurological and preexisting medical condition were analyzed for correlation with eCO.
Results: Mean expired carbonmonoxide, eCO in breath was 2.45 ppm in the study group of urban drivers with mean age 39.96. In 87% of the drivers, eCO was 6ppm. 12.9% of drivers had more than 6 ppm of eCO. 22.8% of drivers exhibited eCO between 3-4 PPM. Analysis of symptoms revealed, tiredness (27%), eye symptoms like irritation and redness (10%), headache (20%), body pain (8%) & fatigue (7%). Significant correlation was observed with body pain (P = 0.04) and fatigue (P=0.03).
Conclusion: Urban drivers are regularly exposed to immense automobile vehicle exhaust which can inflict carbonmonoxide toxicity and impair working capacity.
Keywords: Urban air pollution, Drivers, Carbonmonoxide, Breathanalysis.
References
- Chiew AL, Buckley NA. Carbon monoxide poisoning in the 21st century. Crit Care 2014;18(2):221.
- Chief Medical Officer. Carbon monoxide: the forgotten killer. Department of Health. 2002.PL/CMO/2002/2, PL/CNO/2002/2
- Akyol S, Erdogan S, Idiz N, Celik S, Kaya M, Ucar F. The role of reactive oxygen species and oxidative stress in carbon monoxide toxicity: An in-depth analysis. Redox Rep 2014;19:180–9.
- Penney DG. Chronic carbon monoxide poisoning. In: Penney DG, ed. Carbon monoxide toxicity. London: CRC Press, 2000:393–418.
- Raub JA, Mathieu-Nolf M, Hampson NB, Thom SR. Carbon monoxide poisoning--a public health perspective. Toxicol 2000;7;145(1):1-14.
- Keleş A, Demircan A, Kurtoğlu G. Carbon monoxide poisoning: how many patients do we miss? Eur J Emerg Med 2008;15(3):154-7. doi: 10.1097/MEJ.0b013e3282efd519
[Google Scholar] - Thom SR, Taber RL, Mendiguren II, Clark JM, Hardy KR, Fisher AB. Delayed neuropsychologicsl sequelae after carbon monoxide poisoning: prevention by treatment with hyperbaric oxygen. Ann Emerg Med 1995;25:474–80.
- Amitai Y, Zlotogorski Z, Golan-Katzav V, Wexler A, Gross D. Neuropsychological impairment from acute low-level exposure to carbon monoxide. Arch Neurol 1998;55:845–8.
- Ryan CM. Memory disturbances following chronic, low-level carbon monoxide exposure. Arch Clin Neuropsychol 1990;5:59–67.
- Burnett RT, Dales RE, Brook JR, , Raizenne ME, Krewski D. Association between ambient carbon monoxide levels and hospitalizations for congestive heart failure in the elderly in 10 Canadian cities. Epidemiol 1997;8:162–7.
- WHO. Air quality guidelines: Global update 2005. World Health Organization Report WHO/SDE/PHE/OEH/06.02.
- Lawin H, Fanou LA, Kpangon AA. Comparison of motorcycle taxi driver's respiratory health using an air quality standard for carbon monoxide in ambient air: a pilot survey in Benin. Pan Afr Med J 2018;30:113.
- Heckerling PS. Occult carbon monoxide poisoning: a cause of winter headache. Am J Emerg Med 1987;5(3):201-4.
- da Silva LA, Robazzi ML, Terra Fde S. Relation between workplace accidents and the levels of carboxyhemoglobin in motorcycle taxi drivers. Rev Lat Am Enfermagem 2013;21(5):1119-26.
- Abelsohn A, Sanborn MD, Jessiman BJ, Weir E. Identifying and managing adverse environmental health effects: 6. Carbon monoxide poisoning. CMAJ 2002;166(13):1685-90.
- Eberhardt, M., Powell, A., Bonfante, G., Rupp, V., Guarnaccia, J. R., Heller, M., & Reed, J. Noninvasive measurement of carbon monoxide levels in ED patients with headache. J Med Toxicol 2006;2(3):89-92.
- Ryan CM. Memory disturbances following chronic, low-level carbon monoxide exposure. Arch Clin Neuropsychol 1990;5:59–67.
- Mohammad Javad Golhosseini, Hossein Kakooei, Seyed Jamaleddin Shahtaheri, Kamal Azam, Davood Panahi. Occupational Exposure to Carbon Monoxide of Taxi Drivers in Tehran, Iran. Int J Occup Hyg 2011;3(2):56-62.
- Nair AJ, Nandini M, Adappa S, Mahabala C. Carbon monoxide exposure among police officers working in a traffic dense region of Southern India. Toxicol Ind Health 2017;33(1):46-52.
- Cunnington AJ, Hormbrey CJ. Breath analysis to detect recent exposure to carbon monoxide. Postgrad Med J 2002;78:233-8.
- Air quality criteria for carbon monoxide. Washington, DC. US Environmental Protection Agency, Office of Research and Development, 1991 (publication no.EPA-600/B-90/045F).
- Saksena S, Quang TN, Nguyen T, Dang PN, Flachsbart P. Commuters' exposure to particulate matter and carbon monoxide in Hanoi, Vietnam. Transportation Research Part D: Transport Environ 2008;13(3):206-11.
- Cunnington AJ, Hormbrey CJ. Breath analysis to detect recent exposure to carbon monoxide. Postgrad Med J 2002;78:233-8.
- Institute for Environment and Health. IEH assessment on indoor air quality in the home (2): carbon monoxide. Norwich: Page Bros, 1998
- Kaur S, Nieuwenhuijsen MJ. Determinants of Personal Exposure to PM2.5, Ultrafine Particle Counts, and CO in a Transport Microenvironment. Environ Sci Technol 2009;43(13):4737-43.
- Mourali C, Mohan BA, Meerasa SS. Analysis of breath carbon monoxide among urban automobile drivers. Natl J Physiol Pharm Pharmacol 2018;8(6):882-6.
- U.S. Environmental Protection Agency. Quantitative risk and exposure assessment for carbon monoxide - amended. Research Triangle Park, NC: EPA;
- https://www3.epa.gov/ttn/naaqs/standards/co/data/CO- REA-Amended-July2010.pdf
- Morse CI, Pritchard LJ, Wust RC, Jones DA, Degens H. Carbon monoxide inhalation reduces skeletal muscle fatigue resistance. Acta Physiol (Oxf) 2008;192(3):397–401.
- Penney D, Benignus V, Kephalopoulos S. Carbon monoxide. In: WHO Guidelines for Indoor Air Quality: Selected Pollutants. Geneva: World Health Organization; 2010.
- Available from: https://www.ncbi.nlm.nih.gov/books/NBK138710/
- Townsend, C. L., & Maynard, R. L. Effects on health of prolonged exposure to low concentrations of carbon monoxide. Occup Environ Med 2002;59(10):708-11.
- Clarke S, Keshishian C, Murray V. Screening for carbon monoxide exposure in selected patient groups attending rural and urban emergency departments in England: a prospective observational study. BMJ Open 2012;2(6):e000877. Published 2012 Dec 13. doi:10.1136/bmjopen-2012-000877
[Google Scholar] - Whincup P, Papacosta O, Lennon L, Haines A. Carboxyhaemoglobin levels and their determinants in older British men. BMC Public Health 2006;6:189–289.
- Heckerling P, Leikin J, Maturen A. Occult carbon monoxide poisoning: validation of a prediction model. Am J Med 1988;84:251–6.
- Myers RAM, DeFazio A, Kelly MP. Chronic carbonmonoxide exposure: a clinical syndrome detected by neurological tests. J Clin Psychol 1998:54:555-67.
- Neil B. Hampson, Claude A Piantadosi, Stephen RThom, Lindell K. Weaver. Practice recommendations in the diagnosis, management, and prevention of carbon monoxide poisoning. Am J Respir Crit Care Med 2012;186(18):1095-1101.
How to Cite This Article
Vancouver
M C, R BAR, Semmal M. Breathanalysis of expired carbonmonoxide and its correlation with symptoms of toxicity among urban automobile drivers [Internet]. Indian J Clin Anat Physiol. 2019 [cited 2025 Oct 24];6(2):144-147. Available from: https://doi.org/10.18231/j.ijcap.2019.033
APA
M, C., R, B. A. R., Semmal, M. (2019). Breathanalysis of expired carbonmonoxide and its correlation with symptoms of toxicity among urban automobile drivers. Indian J Clin Anat Physiol, 6(2), 144-147. https://doi.org/10.18231/j.ijcap.2019.033
MLA
M, Chitra, R, Baskara Amsath Raja, Semmal, M. "Breathanalysis of expired carbonmonoxide and its correlation with symptoms of toxicity among urban automobile drivers." Indian J Clin Anat Physiol, vol. 6, no. 2, 2019, pp. 144-147. https://doi.org/10.18231/j.ijcap.2019.033
Chicago
M, C., R, B. A. R., Semmal, M.. "Breathanalysis of expired carbonmonoxide and its correlation with symptoms of toxicity among urban automobile drivers." Indian J Clin Anat Physiol 6, no. 2 (2019): 144-147. https://doi.org/10.18231/j.ijcap.2019.033