Evaluation of the diastolic functions of the heart in patients with heart failure after Cardiac Resynchronization Therapy (CRT)


Original Article

Author Details : Naushi Mujeeb*, S K Saiful Haque Zahed, Sujata Gurung

Volume : 8, Issue : 2, Year : 2021

Article Page : 110-115

https://doi.org/10.18231/j.ijcap.2021.026



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Abstract

Background & Aim: Improvement in systolic functions after CRThas been well-established, but the effect on Left Ventricular (LV) diastolic functions is variable and not well established. The aim of this study is to analyze the improvement in diastolic functions of the heart after CRT.
Materials and Methods: Total 67 cases of Heart Failure (HF) eligible for CRT (mean age, 62.5 ± 11.73 years; 54 males and 13 females) with Left Ventricular Ejection Fraction (LVEF) ?35% or New York Heart Association (NYHA) Class II, III / Ambulatory IV (IVA) were included in the study. LVEF, pulsed-wave Doppler (PWD) derived transmitral filling indices (E and A wave velocities, E/A ratio), and peak early diastolic longitudinal myocardial velocity (E´) wave by tissue doppler were measured pre and post CRT and were compared.
Observations and Results: Left Ventricular Ejection Fraction (LVEF) increased >5% (responders) in 42 of 67 patients (62.6%) which was also associated with a reduction in pulsed-wave Doppler (PWD) derived indices that is E velocity, E/A ratio and E/E’ ratio while in non-responders (LVEF<5> Conclusion: Left Ventricular Diastolic functions improved significantly after CRT in responders but not in non responders.
 

Keywords: Cardiac resynchronization therapy, Diastolic functions, Heart failure, New York Heart Association (NYHA).


How to cite : Mujeeb N, Zahed S K S H, Gurung S, Evaluation of the diastolic functions of the heart in patients with heart failure after Cardiac Resynchronization Therapy (CRT). Indian J Clin Anat Physiol 2021;8(2):110-115


Copyright © 2021 by author(s) and Indian J Clin Anat Physiol. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License (creativecommons.org)





Article History

Received : 02-04-2021

Accepted : 13-04-2021

Available online : 06-07-2021


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https://doi.org/10.18231/j.ijcap.2021.026


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